Prior to entering human clinical trials, investigational products are routinely evaluated for safety and efficacy in pre-clinical models to understand how these drugs will perform in humans.  Avogadro LS provides a large range of in vivo studies including in-life and analytical phases to support the decision making and successful advancement of drug candidates

Examples of our safety and efficacy services

• In vivo Efficacy Models including efficacy studies in skin healing, dyslipidemia and analgesic / pain models and evaluations.  Avogadro LS can also develop other pre-clinical efficacy models upon request.
• DMPK involved at different stages of drug discovery and development for determination of efficacy and safety.
• Analysis of drug content in formulation used during toxicology studies (GLP assays).

• Comparison of different anticoagulant associations on haemostasis and biochemical analyses in feline blood specimens.  Journal of Feline Medicine and Surgery (2016).
  Granat , et. al.

• Model of Induced Fever in Pig: Model Validation
  Arnaud JP, et al.

• Model of Induced Fever in Pig: Comparison of Anti-Pyretic Activities of Ketoprofen and Aspirin.
  Arnaud JP, et al.